Rosehip Seed Oil

Cold-pressed from the seeds of Rosa canina, rosehip oil is rich in linoleic acid, alpha-linolenic acid, and trans-retinoic acid (a natural form of tretinoin). This makes it one of the few plant oils with genuine anti-aging activity — the natural tretinoin content promotes cell turnover and collagen synthesis. It is also high in antioxidants and is used for scars, hyperpigmentation, and fine lines.

Concentration & Usage

Apply 2-4 drops in the evening after water-based serums. Can be used morning (under sunscreen) but the natural retinoid content makes PM use preferred. Cold-pressed, unrefined oil is orange-red. Goes rancid relatively quickly — store in fridge and use within 3-6 months.

Application

Topical (pure oil). Apply 2-4 drops as last step of PM routine. Cold-pressed, unrefined.

Shop Rosehip Seed Oil

99%+ purity · third-party lab tested

Browse →

Mechanism of Action

Natural trans-retinoic acid content (0.01-0.04%) binds RAR receptors in keratinocytes and fibroblasts, promoting cell turnover, collagen type I synthesis, and keratinocyte differentiation at gentle level without retinization. Linoleic acid (44%) supports barrier repair through ceramide synthesis, balances sebum composition (acne-prone skin often deficient). Alpha-linolenic acid (33%) converts to anti-inflammatory metabolites, supports barrier function. Beta-carotene and lycopene provide antioxidant protection and mild photoprotection. Unique combination among plant oils: natural retinoid plus essential fatty acids plus antioxidants — no other oil provides all three. Contains tocopherols. Quickly absorbed. Clinical use: scars, hyperpigmentation, fine lines — subtle but measurable anti-aging effects compared to inert oils.

Regulatory Status

Cosmetic ingredient. Available OTC worldwide.

Risks & Safety

Common

May cause breakouts in oily/acne-prone skin. Goes rancid quickly if not stored properly.

Serious

None.

Rare

Allergic reaction (rose family).

Compare Rosehip Seed Oil With

Research Papers

5
Efficacy and safety of a rosehip seed oil extract in the prevention and treatment of skin lesions in the hands of patients with type 1 diabetes mellitus caused by finger prick blood glucose monitoring; a randomized, open-label, controlled clinical trial.

Published: March 20, 2020

AI Summary

This study was intended to assess the efficacy and safety of a rosehip seed oil (RHO) extract in the prevention and treatment of skin lesions in the hands of patients with type 1 diabetes mellitus (T1DM) caused by finger prick blood glucose monitoring.

Hair Growth-Promoting Effects of Rosehip (Rosa canina L.) Seed Oil in C57BL/6 Mice.

Published: December 30, 2023

AI Summary

Histological analysis revealed significant increases in hair follicle density, hair bulb size, and skin thickness. These findings suggest that RHSO stimulates hair growth and may show promise as a preventive and/or therapeutic agent for hair loss.

Phytotherapeutic evaluation of rosehip seed and olive oils on wound healing: evidence from L929 cell culture and in vivo VEGF/TGF-β analysis.

Published: September 30, 2025

AI Summary

This group also demonstrated the highest vascular endothelial growth factor (VEGF) and transforming growth factor-β (TGF-β) expression levels, greater total antioxidant capacity, and the most effective oxidative stress reduction.

A systematic review on the Rosa canina effect and efficacy profiles.

Published: June 3, 2008

AI Summary

Rose hip, rose hip and seed and rose hip seed, all were negatively monographed by the German Commission E due to insufficient evidence of effects and effectiveness. For various preparations of rose hip and rose hip and seed, antioxidative and antiinflammatory effects have been demonstrated.

Pracaxi oil affects xenobiotic metabolisms, cellular proliferation, and oxidative stress without cytotogenotoxic effects in HepG2/C3A cells.

Published: September 19, 2022

AI Summary

The results showed that the PO did not reduce cell viability at concentrations ranging from 31 to 500 μg/ml. The data indicate that PO has no cytogenotoxic effects and suggest that it activated the PI3/AKT/mTOR cascade of cell growth and proliferation.

Frequently Asked Questions

What is Rosehip Seed Oil used for?

Cold-pressed from the seeds of Rosa canina, rosehip oil is rich in linoleic acid, alpha-linolenic acid, and trans-retinoic acid (a natural form of tretinoin). This makes it one of the few plant oils with genuine anti-aging activity — the natural tretinoin content promotes cell turnover and collagen synthesis. It is also high in antioxidants and is used for scars, hyperpigmentation, and fine lines.

What are the side effects of Rosehip Seed Oil?

Common: May cause breakouts in oily/acne-prone skin. Goes rancid quickly if not stored properly. Serious: None. Rare: Allergic reaction (rose family).

How is Rosehip Seed Oil administered?

Rosehip Seed Oil is administered via topical (pure oil). apply 2-4 drops as last step of pm routine. cold-pressed, unrefined..

Related Nootropics

Adapalene

A third-generation synthetic retinoid originally developed for acne that has significant anti-aging benefits. Adapalene is more stable than tretinoin (resistant to light and oxygen degradation) and better tolerated because it selectively binds to RAR-beta and RAR-gamma receptors rather than all three subtypes. The 0.1% concentration became available OTC in 2016 (Differin), making it the most accessible prescription-strength retinoid.

AcneAnti-Aging

Adapalene

A third-generation synthetic retinoid specifically designed for acne treatment. Unlike tretinoin, adapalene selectively binds RAR-beta and RAR-gamma receptors in the skin, providing potent comedolytic and anti-inflammatory effects with significantly less irritation. It is also more stable in light and with benzoyl peroxide. Differin (0.1%) became OTC in 2016 — the first retinoid available without prescription in the US.

AcneAnti-Aging

Allantoin

A gentle compound found naturally in comfrey root, chamomile, and wheat sprouts that promotes skin healing, moisturization, and the shedding of dead skin cells. Allantoin has been used in dermatology for over 70 years and is one of the most universally tolerated ingredients — it soothes, protects, and promotes recovery without any known irritation potential. Found in everything from diaper cream to post-procedure products.

SoothingHydration

Allantoin

A gentle, non-irritating compound found in comfrey root, chamomile, and wheat sprouts that promotes cell regeneration and has keratolytic and soothing properties. Allantoin is one of the most universally well-tolerated skincare ingredients — it is used in products for newborn babies, post-surgical care, and extremely reactive skin. It softens keratin, promotes wound healing, and reduces irritation from other active ingredients.

SoothingHydration

Aloe Vera

One of the oldest and most recognized soothing ingredients, used for millennia for burns, wounds, and skin irritation. Aloe vera gel contains over 75 active compounds including polysaccharides, vitamins, minerals, and enzymes. It provides immediate cooling, hydration, and anti-inflammatory relief. The evidence is strongest for wound healing, sunburn recovery, and moisturization.

SoothingHydration

Aloe Vera

The gel from Aloe barbadensis leaves has been used for skin healing for over 5,000 years and is backed by modern clinical evidence for wound healing, burn treatment, and anti-inflammatory effects. Aloe gel contains over 75 active compounds including polysaccharides (acemannan), vitamins, minerals, enzymes, and amino acids. It hydrates, soothes, accelerates wound healing, and provides mild antibacterial protection.

SoothingHydration